• Product NameC7 Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen Affinity Purified
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous level of total C7 polyclonal antibody.
• Immunogen Typeprotein
• Immunogen DescriptionRecombinant human Complement component C7 protein (22-270aa)
• Target NameC7
• Alternative Names    C7
• Accession No. Swiss-Prot#: P10643
• UniprotP10643
• Gene ID730;
• Concentration 1.0mg/mL
• Formulation PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Storage Store at -20˚C

• 
  Immunohistochemistry: 1:20 - 1:200

Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor.

[1]Quantitative detection of single amino acid polymorphisms by targeted proteomics." Su Z.D., Sun L., Yu D.X., Li R.X., Li H.X., Yu Z.J., Sheng Q.H., Lin X., Zeng R., Wu J.R. J. Mol. Cell Biol. 3:309-315(2011). [2]Complement C7 deficiency: seven further molecular defects and their associated marker haplotypes." Fernie B.A., Hobart M.J.Hum. Genet. 103:513-519(1998). [3]Molecular bases of C7 deficiency: three different defects."Fernie B.A., Orren A., Sheehan G., Schlesinger M., Hobart M.J.J. Immunol. 159:1019-1026(1997).

• Immunohistochemical analysis of paraffin-embedded human colon cancer using #42095 at dilution of 1:100.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting