• Product NameCD59 glycoprotein Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationCaprylic Acid Ammonium Sulfate Precipitation purified
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous level of total CD59 glycoprotein polyclonal antibody.
• Immunogen Typeprotein
• Immunogen DescriptionRecombinant human CD59 glycoprotein protein
• Target NameCD59 glycoprotein
• Alternative Names    1F5 antigen 20 kDa homologous restriction factor MAC-inhibitory protein MEM43 antigen Membrane attack complex inhibition factor Membrane inhibitor of reactive lysis Protectin CD_antigen=CD59 CD59 MIC11, MIN1, MIN2, MIN3, MSK21
• Accession No. Swiss-Prot#: P13987
• UniprotP13987
• Gene ID966;
• Formulation Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Storage Store at -20˚C

• 
  Immunohistochemistry: 1:20 - 1:200

Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.

[1]CD59, an LY-6-like protein expressed in human lymphoid cells, regulates the action of the complement membrane attack complex on homologous cells.Davies A., Simmons D.L., Hale G., Harrison R.A., Tighe H., Lachmann P.J., Waldmann H.J. Exp. Med. 170:637-6

• Immunohistochemical analysis of paraffin-embedded human placenta using #42110 at dilution of 1:100.
• Immunohistochemical analysis of paraffin-embedded human bladder carcinoma using #42110 at dilution of 1:100.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting