• Product NameHepatitis A virus cellular receptor 2 Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationCaprylic Acid Ammonium Sulfate Precipitation purified
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous level of total Hepatitis A virus cellular receptor 2 polyclonal antibody.
• Immunogen Typeprotein
• Immunogen DescriptionRecombinant human Hepatitis A virus cellular receptor 2 protein
• Target NameHepatitis A virus cellular receptor 2
• Alternative Names    T-cell immunoglobulin and mucin domain-containing protein 3, T-cell membrane protein 3, TIM-3, HAVCR2, TIM3, TIMD3
• Accession No. Swiss-Prot#: Q8TDQ0
• UniprotQ8TDQ0
• Gene ID84868;
• Formulation Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Storage Store at -20˚C

• 
  Immunohistochemistry: 1:20 - 1:200

Regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. May be also involved in T-cell homing. Receptor for LGALS9.

[1] "Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease."Monney L., Sabatos C.A., Gaglia J.L., Ryu A., Waldner H., Chernova T., Manning S., Greenfield E.A., Coyle A.J., Sobel R.A., Freeman G.J., K

• Immunohistochemical analysis of paraffin-embedded mouse aidney using #42200 at dilution of 1:50.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting