Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
[1]The proteomic reactor facilitates the analysis of affinity-purified proteins by mass spectrometry: application for identifying ubiquitinated proteins in human cells."Vasilescu J., Zweitzig D.R., Denis N.J., Smith J.C., Ethier M., Haines D.S., Figeys D. J. Proteome Res. 6:298-305(2007). [2]Complete sequencing and characterization of 21,243 full-length human cDNAs."Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. Sugano S.Nat. Genet. 36:40-45(2004). [3]Two human homeobox genes, c1 and c8: structure analysis and expression in embryonic development." Simeone A., Mavilio F., Acampora D., Giampaolo A., Faiella A., Zappavigna V., D'Esposito M., Pannese M., Russo G., Boncinelli E., Peschle C.Proc. Natl. Acad. Sci. U.S.A. 84:4914-4918(1987).