• Product NameDeoxynucleoside triphosphate triphosphohydrolase SAMHD1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationCaprylic Acid Ammonium Sulfate Precipitation purified
• ApplicationsWB
• Species ReactivityMs
• SpecificityThe antibody detects endogenous level of total Deoxynucleoside triphosphate triphosphohydrolase SAMHD1.
• Immunogen Typeprotein
• Immunogen DescriptionRecombinant Human Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 protein
• Target NameDeoxynucleoside triphosphate triphosphohydrolase SAMHD1
• Alternative Names    Dendritic cell-derived IFNG-induced protein, Monocyte protein 5, SAM domain and HD domain-containing protein 1, SAMHD1, MOP5
• Accession No. Swiss-Prot#: Q9Y3Z3
• UniprotQ9Y3Z3
• Gene ID25939;
• Calculated MW 72kd
• Formulation Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Storage Store at -20˚C

• Western blotting: 1:500 - 1:1000
  

Host restriction nuclease that blocks early-stage virus replication in dendritic and other myeloid cells. May function by reducing the cellular dNTP levels to levels too low for retroviral reverse transcription to occur. May play a role in mediating proinflammatory responses to TNF-alpha signaling.

[1] Identification of human homologue of mouse IFN-gamma induced protein from human dendritic cells.Li N., Zhang W., Cao X.Immunol. Lett. 74:221-224(2000) [2] Molecular and biological characterization of a novel monocyte protein, MOP-5.Takayama K., Yos

• All lanes : Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 antibody at 2ug/ml+293T whole cell lysate Secondary Goat polyclonal to Rabbit IgG at 1/10000 dilution Predicted band size : 72KDa Observed band size:72KDa

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting