• Product NameGanglioside GM2 activator Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationCaprylic Acid Ammonium Sulfate Precipitation purified
• ApplicationsWB
• Species ReactivityHu Ms
• SpecificityThe antibody detects endogenous level of total Ganglioside GM2 activator polyclonal antibody.
• Immunogen Typeprotein
• Immunogen DescriptionRecombinant human Ganglioside GM2 activator protein
• Target NameGanglioside GM2 activator
• Alternative Names    GM2A
• Accession No. Swiss-Prot#: P17900
• UniprotP17900
• Gene ID2760;
• Calculated MW 21kd
• Formulation Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Storage Store at -20˚C

• Western blotting: 1:500 - 1:1000
  

Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3.

[1] "Isolation and expression of a full-length cDNA encoding the human G-M2 activator protein."Xie B., McInnes B., Neote K., Lamhonwah A.-M., Mahuran D.Biochem. Biophys. Res. Commun. 177:1217-1223(1991) [2] "Characterization of full-length cDNAs and th

• All lanes: Ganglioside GM2 activator antibody at 2ug/ml+rat kidney tissue secondary Goat polyclonal to rabbit at 1/10000 dilution predicted band size :21kDa observed band size :21kDa

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting