• Product NameCyclin-dependent kinase 11A Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationCaprylic Acid Ammonium Sulfate Precipitation purified
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous level of total Cyclin-dependent kinase 11A polyclonal antibody.
• Immunogen Typeprotein
• Immunogen DescriptionRecombinant human Cyclin-dependent kinase 11A protein
• Target NameCyclin-dependent kinase 11A
• Alternative Names    CDC2L2, CDC2L3, PITSLREB CDK11A Cell division cycle 2-like protein kinase 2 Cell division protein kinase 11A Galactosyltransferase-associated protein kinase p58/GTA PITSLRE serine/threonine-protein kinase CDC2L2
• Accession No. Swiss-Prot#: Q9UQ88
• UniprotQ9UQ88
• Gene ID728642;
• Calculated MW 87kd
• Formulation Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Storage Store at -20˚C

• Western blotting: 1:500 - 1:1000
  

Appears to play multiple roles in cell cycle progression, cytokinesis and apoptosis. The p110 isoforms have been suggested to be involved in pre-mRNA splicing, potentially by phosphorylating the splicing protein SFRS7. The p58 isoform may act as a negative regulator of normal cell cycle progression.

[1] "Molecular cloning and expression of alternatively spliced PITSLRE protein kinase isoforms." Xiang J., Lahti J.M., Grenet J.A., Easton J.B., Kidd V.J. J. Biol. Chem. 269:15786-15794(1994) [PubMed: 8195233] [Abstract] Cited for: NUCLEOTIDE SEQUENCE

• Cyclin-dependent kinase 11A antibody at at 2ug/ml+293T whole cell lysate SecondaryGoat polyclonal to Rabbit IgG at 1/15000 dilution Predicted band size : 87 kDa Observed band size: 87kDa

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting