Multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. In plasma, it carries the vitamin D sterols and prevents polymerization of actin by binding its monomers. DBP associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes.
[1] Serum vitamin D-binding protein is a third member of the albumin and alpha fetoprotein gene family.Cooke N.E., David E.V.J. Clin. Invest. 76:2420-2424(1985) [2] Human group-specific component (Gc) is a member of the albumin family.Yang F., Brune J.
