• Product NameTumor necrosis factor receptor superfamily member 10D Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationCaprylic Acid Ammonium Sulfate Precipitation purified
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous level of total Tumor necrosis factor receptor superfamily member 10D polyclonal antibody.
• Immunogen Typeprotein
• Immunogen DescriptionRecombinant human Tumor necrosis factor receptor superfamily member 10D protein
• Target NameTumor necrosis factor receptor superfamily member 10D
• Alternative Names    UNQ251/PRO288, DCR2, TRAILR4, TRUNDD, TNFRSF10D, Decoy receptor 2, DcR2, TNF-related apoptosis-inducing ligand receptor 4, TRAIL receptor 4, TRAIL-R4, TRAIL receptor with a truncated death domain, CD_antigen=CD264
• Accession No. Swiss-Prot#: Q9UBN6
• UniprotQ9UBN6
• Gene ID8793;
• Formulation Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Storage Store at -20˚C

• 
  Immunohistochemistry: 1:20 - 1:200

Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to Ref.1, it cannot but according to Ref.2, it can induce the NF-kappa-B pathway.

[1] "A novel receptor for Apo2L/TRAIL contains a truncated death domain."Marsters S.A., Sheridan J.P., Pitti R.M., Huang A., Skubatch M., Baldwin D., Yuan J., Gurney A., Goddard A.D., Godowski P., Ashkenazi A.Curr. Biol. 7:1003-1006(1997) [2] "The nove

• Immunohistochemical analysis of paraffin-embeded human kidney using #42499 at dilution of 1:100.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting