• Product NameSubstance-P receptor Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationCaprylic Acid Ammonium Sulfate Precipitation purified
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous level of total Substance-P receptor polyclonal antibody.
• Immunogen Typeprotein
• Immunogen DescriptionRecombinant human Substance-P receptor protein
• Target NameSubstance-P receptor
• Alternative Names    NK1R, TAC1R, TACR1, NK-1 receptor, NK-1R, Tachykinin receptor 1, SPR
• Accession No. Swiss-Prot#: P25103
• UniprotP25103
• Gene ID6869;
• Formulation Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Storage Store at -20˚C

• 
  Immunohistochemistry: 1:20 - 1:200

This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K.

[1] "Molecular cloning, structural characterization and functional expression of the human substance P receptor."Takeda Y., Chou K.B., Takeda J., Sachais B.S., Krause J.E.Biochem. Biophys. Res. Commun. 179:1232-1240(1991) [2] "Isolation and characteris

• Immunohistochemical analysis of paraffin-embedded human spleem using #42508 at dilution of 1:100 .

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting