• Product NameFilamin B antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAffinity purified by Protein A.
• ApplicationsWB IF
• Species ReactivityHu
• Immunogen TypeRecombinant protein
• Immunogen DescriptionRecombinant protein fragment contain a sequence corresponding to a region within amino acids 30 and 239 of Filamin B
• Target NameFilamin B
• Accession No. Swiss-Prot:O75369
  Gene ID:2317
• UniprotO75369
• Gene ID2317;
• Concentration 10mg/ml
• Formulation Supplied in 1XPBS, 1%BSA, 20% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
• Storage Store at -20˚C for long term preservation (recommended). Store at 4˚C for short term use.

• Predicted MW: 278kd
  Western blotting: 1:500-1:3000
  Immunofluorescence: 1:100-1:200
  

This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3; boomerang dysplasia; autosomal dominant Larsen syndrome; and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq]

• Sample (30 ug of whole cell lysate)
  A: A431
  5% SDS PAGE
  Primary antibody diluted at 1: 1000
• Confocal immunofluorescence analysis (Olympus FV10i) of paraformaldehyde-fixed HeLa, using Filamin B antibody (Green) at 1: 500 dilution and alpha-tubulin antibody (Red) at 1: 2500.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting