• Product NameDPP8 Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen Affinity Purified
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous level of total DPP8 polyclonal antibody.
• Immunogen Typeprotein
• Immunogen DescriptionRecombinant human Dipeptidyl peptidase 8 protein (10-230aa)
• Target NameDPP8
• Alternative Names    DP8, Dipeptidyl peptidase IV-related protein 1, DPRP-1, Dipeptidyl peptidase VIII, DPP VIII, Prolyl dipeptidase DPP8, DPP8, DPRP1, MSTP097, MSTP135, MSTP141
• Accession No. Swiss-Prot#: Q6V1X1
• UniprotQ6V1X1
• Gene ID54878;
• Concentration 1.0mg/mL
• Formulation PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Storage Store at -20˚C

• 
  Immunohistochemistry: 1:20 - 1:200

Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2. May play a role in T-cell activation and immune function.

[1]"Novel isoindoline compounds for potent and selective inhibition of prolyl dipeptidase DPP8." Jiaang W.-T., Chen Y.-S., Hsu T., Wu S.-H., Chien C.-H., Chang C.-N., Chang S.-P., Lee S.-J., Chen X. Bioorg. Med. Chem. Lett. 15:687-691(2005). [2]"Purification and characterization of human prolyl dipeptidase DPP8 in Sf9 insect cells." Chen Y.-S., Chien C.-H., Goparaju C.M., Hsu J.T.-A., Liang P.-H., Chen X.Protein Expr. Purif. 35:142-146(2004). [3]"Structural requirements for catalysis, expression, and dimerization in the CD26/DPIV gene family." Ajami K., Abbott C.A., Obradovic M., Gysbers V., Kaehne T., McCaughan G.W., Gorrell M.D.Biochemistry 42:694-701(2003).

• Immunohistochemical analysis of paraffin-embedded human endometrial cancer using #42659 at dilution of 1:100.
• Immunohistochemical analysis of paraffin-embedded human testicle using #42659 at dilution of 1:100.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting