• Product NameBIRC8 Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen Affinity Purified
• ApplicationsWB
• Species ReactivityHu Ms
• SpecificityThe antibody detects endogenous level of total BIRC8 polyclonal antibody.
• Immunogen Typeprotein
• Immunogen DescriptionRecombinant human Baculoviral IAP repeat-containing protein 8 protein(1-236aa)
• Target NameBIRC8
• Alternative Names    Inhibitor of apoptosis-like protein 2, IAP-like protein 2, ILP-2, Testis-specific inhibitor of apoptosis, BIRC8, ILP2
• Accession No. Swiss-Prot#: Q96P09
• UniprotQ96P09
• Calculated MW 27kd
• Concentration 1.0mg/mL
• Formulation PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Storage Store at -20˚C

• Western blotting: 1:500 - 1:2000
  

Protects against apoptosis mediated by BAX.

[1]The BIR domain of IAP-like protein 2 is conformationally unstable: implications for caspase inhibition."Shin H., Renatus M., Eckelman B.P., Nunes V.A., Sampaio C.A., Salvesen G.S. Biochem. J. 385:1-10(2005). [2]The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."The MGC Project TeamGenome Res. 14:2121-2127(2004). [3]Molecular cloning of ILP-2, a novel member of the inhibitor of apoptosis protein family." Richter B.W.M., Mir S.S., Eiben L.J., Lewis J., Reffey S.B., Frattini A., Tian L., Frank S., Youle R.J., Nelson D.L., Notarangelo L.D., Vezzoni P., Fearnhead H.O., Duckett C.S..Mol. Cell. Biol. 21:4292-4301(2001).

• All lanes: Baculoviral IAP repeat-containing protein 8 antibody at 6ug/ml+mouse brain tissue secondary Goat polyclonal to rabbit at 1/10000 dilution predicted band size :27kDa observed band size :27kDa

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting