Catalyzes the deimination of arginine residues of proteins.
[1]The DNA sequence and biological annotation of human chromosome 1. Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K. expand/collapse author list Bentley D.R. Nature 441:315-321(2006). [2]Comparative analysis of the mouse and human peptidylarginine deiminase gene clusters reveals highly conserved non-coding segments and a new human gene, PADI6. Chavanas S., Mechin M.-C., Takahara H., Kawada A., Nachat R., Serre G., Simon M. Gene 330:19-27(2004). [3]Human peptidylarginine deiminase type II: molecular cloning, gene organization, and expression in human skin. Ishigami A., Ohsawa T., Asaga H., Akiyama K., Kuramoto M., Maruyama N. Arch. Biochem. Biophys. 407:25-31(2002).