• Product NameATIC Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsWB IHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total ATIC protein.
• Immunogen Typeprotein
• Immunogen DescriptionFusion protein of human ATIC
• Target NameATIC
• Alternative Names    PURH; AICAR; AICARFT; IMPCHASE; HEL-S-70p
• Accession No. Swiss-Prot#: P31939
  Gene ID: 471
• UniprotP31939
• Gene ID471;
• Calculated MW 65kd
• Concentration 2mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Western blotting: 1:200-1:1000
  Immunohistochemistry: 1:25-1:100

This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria.?

• Gel: 6%SDS-PAGE
  Lysate: 40 μg
  Lane: 231 cell
  Primary antibody: 1/350 dilution
  Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution
  Exposure time: 20 seconds
• Immunohistochemical analysis of paraffin-embedded Human brain tissue using #42810 at dilution 1/25,

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting