• Product NameRecombinant Human PKM
• Brief DescriptionRecombinant Protein
• Immunogen DescriptionFusion protein corresponding to a region derived from 11-221 amino acids of human pyruvate kinase, muscle
• Target Namepyruvate kinase, muscle
• Alternative Names    PK3; TCB; OIP3; PKM2; CTHBP; THBP1; HEL-S-30
• Accession No. Swissprot:P14618
  Gene Accession:BC007640
• UniprotP14618
• Gene ID5315;
• Storage -20~-80˚C, pH 7.6 PBS

This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.

Note: For in vitro research use only, not for diagnostic or therapeutic use. This product is not a medical device.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting