• Product NameRecombinant Human APIP
• Brief DescriptionRecombinant Protein
• Immunogen DescriptionFull length fusion protein
• Target NameAPAF1 interacting protein
• Alternative Names    APIP2, CGI29, CGI-29, MMRP19, dJ179L10.2
• Accession No. Swissprot:Q96GX9
  Gene Accession:BC008440
• UniprotQ96GX9
• Gene ID51074;
• Storage -20~-80˚C, pH 7.6 PBS

APIP is an APAF1 (MIM 602233)-interacting protein that acts as a negative regulator of ischemic/hypoxic injury.The protein highly expressed in skeletal muscle and heart and binds to the CARD of Apaf-1 in competition with caspase-9. Exogenous APIP inhibits cytochrome c-induced activation of caspase-3 and caspase-9, and suppresses cell death triggered by mitochondrial apoptotic stimuli through inhibiting the downstream activity of cytochrome c released from mitochondria.

Note: For in vitro research use only, not for diagnostic or therapeutic use. This product is not a medical device.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting