• Product NameRecombinant Human CTNNA1
• Brief DescriptionRecombinant Protein
• Immunogen DescriptionFusion protein corresponding to C terminal 300 amino acids of human catenin (cadherin-associated protein), alpha 1, 102kDa
• Target NameCatenin (cadherin-associated protein), alpha 1, 102kDa
• Alternative Names    CAP102
• Accession No. Swissprot:P35221
  Gene Accession:BC031262
• UniprotP35221
• Gene ID1495;
• Storage -20~-80˚C, pH 7.6 PBS

Catenin alpha-1?is a?protein?that in humans is encoded by the?CTNNA1?gene. Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components.

Note: For in vitro research use only, not for diagnostic or therapeutic use. This product is not a medical device.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting