• Product NameRecombinant Human CUL7
• Brief DescriptionRecombinant Protein
• Immunogen DescriptionFusion protein corresponding to a region derived from 1399-1698 amino acids of human CUL7
• Target Namecullin 7
• Alternative Names    3M1; KIAA0076; dJ20C7.5
• Accession No. Swissprot:Q14999
  Gene Accession:BC033647
• UniprotQ14999
• Gene ID9820;
• Storage -20~-80˚C, pH 7.6 PBS

The protein encoded by this gene is a component of an E3 ubiquitin-protein ligase complex. The encoded protein interacts with TP53, CUL9, and FBXW8 proteins. Defects in this gene are a cause of 3M syndrome type 1 (3M1). Two transcript variants encoding different isoforms have been found for this gene. CUL-7 is highly expressed in fetal kidney and adult skeletal muscle in addition to abundant expression in fetal brain, and adult pancreas, kidney, placenta and heart. It is also detected in trophoblasts, lymphoblasts, osteoblasts, chondrocytes and skin fibroblasts.

Note: For in vitro research use only, not for diagnostic or therapeutic use. This product is not a medical device.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting