• Product NameRecombinant Human GDF15
• Brief DescriptionRecombinant Protein
• Immunogen DescriptionFusion protein corresponding to a region derived from 195-308 amino acids of human growth differentiation factor 15
• Target Namegrowth differentiation factor 15
• Alternative Names    PDF, MIC1, PLAB, MIC-1, NAG-1, PTGFB, GDF-15
• Accession No. Swissprot:Q99988
  Gene Accession:BC000529
• UniprotQ99988
• Gene ID9518;
• Storage -20~-80˚C, pH 7.6 PBS

Bone morphogenetic proteins (e.g., BMP9; MIM 605120) are members of the transforming growth factor-beta (see TGFB1; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein. GDF15 mRNA is most abundant in the liver, with lower levels seen in some other tissues. Its expression in liver can be significantly up-regulated in during injury of organs such as liver, kidney, heart and lung.

Note: For in vitro research use only, not for diagnostic or therapeutic use. This product is not a medical device.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting