• Product NameRecombinant Human HDAC1
• Brief DescriptionRecombinant Protein
• Immunogen DescriptionFusion protein corresponding to a region derived from 9-300 amino acids of human HDAC1
• Target Namehistone deacetylase 1
• Alternative Names    HD1; RPD3; GON-10; RPD3L1
• Accession No. Swissprot:Q13547
  Gene Accession:BC000301
• UniprotQ13547
• Gene ID3065;
• Storage -20~-80˚C, pH 7.6 PBS

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.

Note: For in vitro research use only, not for diagnostic or therapeutic use. This product is not a medical device.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting