• Product NameRecombinant Human IRAK4
• Brief DescriptionRecombinant Protein
• Immunogen DescriptionFusion protein corresponding to a region derived from 186-454 amino acids of human interleukin-1 receptor-associated kinase 4
• Target Nameinterleukin-1 receptor-associated kinase 4
• Alternative Names    IPD1; REN64; IRAK-4; NY-REN-64
• Accession No. Swissprot:Q9NWZ3
  Gene Accession:BC013316
• UniprotQ9NWZ3
• Gene ID51135;
• Storage -20~-80˚C, pH 7.6 PBS

This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.

Note: For in vitro research use only, not for diagnostic or therapeutic use. This product is not a medical device.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting