• Product NameRecombinant Human LAT2
• Brief DescriptionRecombinant Protein
• Immunogen DescriptionFusion protein corresponding to a region derived from 27-243 amino acids of human linker for activation of T cells family, member 2
• Target Namelinker for activation of T cells family, member 2
• Alternative Names    LAB, NTAL, WSCR5, WBSCR5, HSPC046, WBSCR15
• Accession No. Swissprot:Q9GZY6
  Gene Accession:BC001609
• UniprotQ9GZY6
• Gene ID7462;
• Storage -20~-80˚C, pH 7.6 PBS

This gene is one of the contiguous genes at 7q11.23 commonly deleted in Williams syndrome, a multisystem developmental disorder. This gene consists of at least 14 exons, and its alternative splicing generates 3 transcript variants, all encoding the same protein. Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2.

Note: For in vitro research use only, not for diagnostic or therapeutic use. This product is not a medical device.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting