• Product NameRecombinant Human PRMT7
• Brief DescriptionRecombinant Protein
• Immunogen DescriptionFusion protein corresponding to a region derived from 526-692 amino acids of human protein arginine methyltransferase 7
• Target NameProtein arginine methyltransferase 7
• Accession No. Swissprot:Q9NVM4
  Gene Accession:BC000146
• UniprotQ9NVM4
• Gene ID54496;
• Storage -20~-80˚C, pH 7.6 PBS

Protein arginine methyltransferase 7?is a?protein?that in humans is encoded by the?PRMT7?gene.?Arginine?methylation?is an apparently irreversible protein modification catalyzed by arginine methyltransferases, such as PMT7, using?S-adenosylmethionine?(AdoMet) as the methyl donor. Arginine methylation is implicated in?signal transduction, RNA transport, and?RNA splicing. May be involved in etoposide-induced cytotoxicity, a chemotherapeutic agent frequently used for testicular cancer and small-cell lung cancer that can cause cytotoxicity in the treatment of other cancers. Down-regulation confers increased sensitivity to the Top1 inhibitor camptothecin (CPT).

Note: For in vitro research use only, not for diagnostic or therapeutic use. This product is not a medical device.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting