• Product NameRecombinant Human ACVR1C
• Brief DescriptionRecombinant Protein
• Immunogen DescriptionFusion protein corresponding to a region derived from 195-485 amino acids of human activin A receptor, type IC
• Target Nameactivin A receptor, type IC
• Alternative Names    ALK7; ACVRLK7
• Accession No. Swissprot:Q8NER5
  Gene Accession:BC022530
• UniprotQ8NER5
• Gene ID130399;
• Storage -20~-80˚C, pH 7.6 PBS

ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).

Note: For in vitro research use only, not for diagnostic or therapeutic use. This product is not a medical device.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting