• Product NameRecombinant Human EPS15L1
• Brief DescriptionRecombinant Protein
• Immunogen DescriptionFusion protein corresponding to C terminal 250 amino acids of human epidermal growth factor receptor pathway substrate 15-like 1
• Target Nameepidermal growth factor receptor pathway substrate 15-like 1
• Alternative Names    EPS15R
• Accession No. Swissprot:Q9UBC2
  Gene Accession:BC131590
• UniprotQ9UBC2
• Gene ID58513;
• Storage -20~-80˚C, pH 7.6 PBS

Epidermal growth factor receptor substrate 15-like 1?is a?protein?that in humans is encoded by the?EPS15L1gene. Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2. Interacts with EPS15, AGFG1/HRB and AGFG2/HRBL. Associates with the clathrin-associated adapter protein complex 2 (AP-2) By similarity. Interacts with FCHO1. Interacts with FCHO2. Interacts (via EH domains) with DAB2.

Note: For in vitro research use only, not for diagnostic or therapeutic use. This product is not a medical device.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting