• Product NameRecombinant Human STK17B
• Brief DescriptionRecombinant Protein
• Immunogen DescriptionFusion protein corresponding to a region derived from 33-293 amino acids of human serine/threonine kinase 17b
• Target Nameserine/threonine kinase 17b
• Alternative Names    DRAK2
• Accession No. Swissprot:O94768
  Gene Accession:BC016040
• UniprotO94768
• Gene ID9262;
• Storage -20~-80˚C, pH 7.6 PBS

The full-length?STK17B?cDNA clone encodes a deduced 372-amino acid protein with a molecular mass of 42.34 kD. The putative kinase domain is located at the N terminus and contains all 11 subdomains conserved among ser/thr kinases. STK17A and?STK17B?share 59.7% amino acid identity.?Northern blot analysis revealed that STK17B was expressed in various tissues, such as heart, placenta, liver, and pancreas, as different-sized transcripts, presumably due to differences in the 3-prime untranslated region. Transient transfection of COS-7 cells showed that STK17B localized in nuclei. Phosphorylates myosin light chains. Acts as a positive regulator of apoptosis.

Note: For in vitro research use only, not for diagnostic or therapeutic use. This product is not a medical device.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting