• Product NameRecombinant Human ABI3BP
• Brief DescriptionRecombinant Protein
• Immunogen DescriptionFusion protein corresponding to a region derived from 731-930 amino acids of human ABI family, member 3 (NESH) binding protein
• Target NameABI family, member 3 (NESH) binding protein
• Alternative Names    TARSH; NESHBP
• Accession No. Swissprot:Q7Z7G0
  Gene Accession:BC030221
• UniprotQ7Z7G0
• Gene ID25890;
• Storage -20~-80˚C, pH 7.6 PBS

A target of NESH-SH3/Abi3bp (TARSH) was originally identified as an SH3 domain-binding molecule of the NESH-SH3/Abi3 protein that is involved in Rac-dependent actin polymerization. In recent studies, TARSH gene expression was dramatically induced in mouse embryonic fibroblasts (MEFs) replicative senescence and suppressed in human lung carcinoma specimens and thyroid carcinomas. However, the molecular mechanism underlying the regulation of TARSH in tumorigenesis remains unclear.

Note: For in vitro research use only, not for diagnostic or therapeutic use. This product is not a medical device.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting