• Product NameRecombinant Human AIFM3
• Brief DescriptionRecombinant Protein
• Immunogen DescriptionFusion protein corresponding to C terminal 250 amino acids of human apoptosis-inducing factor, mitochondrion-associated, 3
• Target Nameapoptosis-inducing factor, mitochondrion-associated, 3
• Alternative Names    AIFL
• Accession No. Swissprot:Q96NN9
  Gene Accession:BC032485
• UniprotQ96NN9
• Gene ID150209;
• Storage -20~-80˚C, pH 7.6 PBS

AIFL (apoptosis-inducing factor-like), also known as AIFM3 (apoptosis-inducing factor, mitochondrion-associated, 3), is a 605 amino acid protein that localizes to the mitochondrion and contains one rieske domain. Expressed ubiquitously in tissues including liver, thymus, ovary, bone marrow and cerebral cortex, AIFL functions to induce apoptosis, specifically through a caspase-dependent pathway, and may also play a role in the modulation of mitochondrial membrane potential. Multiple isoforms of AIFL exist due to alternative splicing events. The gene encoding AIFL maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome.

Note: For in vitro research use only, not for diagnostic or therapeutic use. This product is not a medical device.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting