• Product NameRecombinant Human FAIM3
• Brief DescriptionRecombinant Protein
• Immunogen DescriptionFusion protein corresponding to a region derived from 18-251 amino acids of human Fas apoptotic inhibitory molecule 3
• Target NameFas apoptotic inhibitory molecule 3
• Alternative Names    FCMR; TOSO
• Accession No. Swissprot:O60667
  Gene Accession:BC006401
• UniprotO60667
• Gene ID9214;
• Storage -20~-80˚C, pH 7.6 PBS

Fc receptors specifically bind to the Fc region of immunoglobulins (Igs) to mediate the unique functions of each Ig class. FAIM3 encodes an Fc receptor for IgM. May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream.

Note: For in vitro research use only, not for diagnostic or therapeutic use. This product is not a medical device.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting