• Product NameRecombinant Human HSD17B12
• Brief DescriptionRecombinant Protein
• Immunogen DescriptionFusion protein corresponding to a region derived from 25-180 amino acids of human hydroxysteroid (17-beta) dehydrogenase 12
• Target Namehydroxysteroid (17-beta) dehydrogenase 12
• Alternative Names    KAR; SDR12C1
• Accession No. Swissprot:Q53GQ0
  Gene Accession:BC012043
• UniprotQ53GQ0
• Gene ID51144;
• Storage -20~-80˚C, pH 7.6 PBS

This gene encodes a very important 17beta-hydroxysteroid dehydrogenase (17beta-HSD) that converts estrone into estradiol in ovarian tissue. This enzyme is also involved in fatty acid elongation. Catalyzes the transformation of estrone (E1) into estradiol (E2), suggesting a central role in estrogen formation. Its strong expression in ovary and mammary gland suggest that it may constitute the major enzyme responsible for the conversion of E1 to E2 in women.

Note: For in vitro research use only, not for diagnostic or therapeutic use. This product is not a medical device.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting