• Product NameRecombinant Human PRAME
• Brief DescriptionRecombinant Protein
• Immunogen DescriptionFusion protein corresponding to a region derived from 260-509 amino acids of human PRAME
• Target Namepreferentially expressed antigen in melanoma
• Alternative Names    MAPE; OIP4; CT130; OIP-4
• Accession No. Swissprot:P78395
  Gene Accession:BC014074
• UniprotP78395
• Gene ID23532;
• Storage -20~-80˚C, pH 7.6 PBS

This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.

Note: For in vitro research use only, not for diagnostic or therapeutic use. This product is not a medical device.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting