• Product NameRecombinant Human GNB2L1
• Brief DescriptionRecombinant Protein
• Immunogen DescriptionFusion protein corresponding to C terminal 193 amino acids of human guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
• Target Nameguanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
• Alternative Names    H12.3; HLC-7; PIG21; RACK1; Gnb2-rs1
• Accession No. Swissprot:P63244
  Gene Accession:BC000214
• UniprotP63244
• Gene ID10399;
• Storage -20~-80˚C, pH 7.6 PBS

RACK1 (receptor for activated C kinase 1) is a 317 amino acid G protein b subunit-like protein that functions as a RACK and inhibits the activity of Src tyrosine kinases. In response to PKC activation, the intracellular localization of RACK1 and PKC bII changes, and RACK1 and PKC bII co-localize to the same sites. RACK1 is therefore thought to be a shuttling protein for PKC bII. A deficit in RACK1 may be associated with impaired PKC activation in the aging brain.?

Note: For in vitro research use only, not for diagnostic or therapeutic use. This product is not a medical device.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting