• Product NameRecombinant Human UACA
• Brief DescriptionRecombinant Protein
• Immunogen DescriptionFusion protein corresponding to C terminal 200 amino acids of human uveal autoantigen with coiled-coil domains and ankyrin repeats
• Target Nameuveal autoantigen with coiled-coil domains and ankyrin repeats
• Alternative Names    NUCLING
• Accession No. Swissprot:Q9BZF9
  Gene Accession:BC113407
• UniprotQ9BZF9
• Gene ID55075;
• Storage -20~-80˚C, pH 7.6 PBS

Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity).

Note: For in vitro research use only, not for diagnostic or therapeutic use. This product is not a medical device.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting