• Product NameHPD Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsWB IHC
• Species ReactivityHu Ms
• SpecificityThe antibody detects endogenous levels of total HPD protein.
• Immunogen Typeprotein
• Immunogen DescriptionFusion protein of human HPD
• Target NameHPD
• Alternative Names    PPD; 4HPPD; GLOD3; 4-HPPD; HPPDASE
• Accession No. Swiss-Prot#: P32754
  Gene ID: 3242
• UniprotP32754
• Gene ID3242;
• Calculated MW 45kd
• Concentration 1mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Western blotting: 1:200-1:1000
  Immunohistochemistry: 1:25-1:100

The protein encoded by this gene is an enzyme in the catabolic pathway of tyrosine. The encoded protein catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisate. Defects in this gene are a cause of tyrosinemia type 3 (TYRO3) and hawkinsinuria (HAWK). Two transcript variants encoding different isoforms have been found for this gene.

• Gel: 8%SDS-PAGE
  Lysate: 40 μg
  Lane: Mouse liver tissue
  Primary antibody: 1/400 dilution
  Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution
  Exposure time: 20 seconds
• Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue using #43066 at dilution 1/20. (Original magnification: ¡Á200)

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting