• Product NameRecombinant Human ATIC
• Brief DescriptionRecombinant Protein
• Immunogen DescriptionFusion protein corresponding to C terminal 200 amino acids of human ATIC
• Target Name5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
• Alternative Names    PURH; AICAR; AICARFT; IMPCHASE; HEL-S-70p
• Accession No. Swissprot:P31939
  Gene Accession:BC008879
• UniprotP31939
• Gene ID471;
• Storage -20~-80˚C, pH 7.6 PBS

This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria.?

Note: For in vitro research use only, not for diagnostic or therapeutic use. This product is not a medical device.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting