• Product NameRecombinant Human BCL7A
• Brief DescriptionRecombinant Protein
• Immunogen DescriptionFusion protein corresponding to N terminal 187 amino acids of human BCL7A
• Target NameB-cell CLL/lymphoma 7A
• Alternative Names    BCL7
• Accession No. Swissprot:Q4VC05
  Gene Accession:BC113627
• UniprotQ4VC05
• Gene ID605;
• Storage -20~-80˚C, pH 7.6 PBS

This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene.

Note: For in vitro research use only, not for diagnostic or therapeutic use. This product is not a medical device.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting