• Product NameSETMAR Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsWB IHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total SETMAR protein.
• Immunogen Typeprotein
• Immunogen DescriptionFusion protein of human SETMAR
• Target NameSETMAR
• Alternative Names    Mar1; HsMar1; METNASE
• Accession No. Swiss-Prot#: Q53H47
  Gene ID: 6419
• UniprotQ53H47
• Gene ID6419;
• Calculated MW 78kd
• Concentration 1mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Western blotting: 1:200-1:1000
  Immunohistochemistry: 1:20-1:100

This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain.

• Gel: 6%SDS-PAGE
  Lysate: 40 μg
  Lane: Jurkat cell
  Primary antibody: 1/400 dilution
  Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution
  Exposure time: 30 seconds
• Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using #43086 at dilution 1/20.
• Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using #43086 at dilution 1/20.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting