• Product NameRecombinant Human BTK
• Brief DescriptionRecombinant Protein
• Immunogen DescriptionFusion protein corresponding to a region derived from 460-659 amino acids of human BTK
• Target NameBruton tyrosine kinase
• Alternative Names    AT; ATK; BPK; XLA; IMD1; AGMX1; PSCTK1
• Accession No. Swissprot:Q06187
  Gene Accession:BC109079
• UniprotQ06187
• Gene ID695;
• Storage -20~-80˚C, pH 7.6 PBS

The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.

Note: For in vitro research use only, not for diagnostic or therapeutic use. This product is not a medical device.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting