• Product NameDNASE2 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total DNASE2 protein.
• Immunogen Typepeptide
• Immunogen DescriptionSynthetic peptide of human DNASE2
• Target NameDNASE2
• Alternative Names    DNL; DNL2; DNASE2A
• Accession No. Swiss-Prot#: O00115
  Gene ID: 1777
• UniprotO00115
• Gene ID1777;
• Calculated MW 40kd
• Concentration 0.7mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Western blotting: 1:200-1:1000
  Immunohistochemistry: 1:30-1:150

This gene encodes a member of the DNase family. The protein, located in the lysosome, hydrolyzes DNA under acidic conditions and mediates the breakdown of DNA during erythropoiesis and apoptosis. Two codominant alleles have been characterized, DNASE2*L (low activity) and DNASE2*H (high activity), that differ at one nucleotide in the promoter region. The DNASE2*H allele is represented in this record.

• Gel: 12%SDS-PAGE
  Lysate: 40 μg
  Lane: HEPG2 cell
  Primary antibody: 1/200 dilution
  Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution
  Exposure time: 1MIN

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting