• Product NameMACC1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total MACC1 protein.
• Immunogen Typepeptide
• Immunogen DescriptionSynthetic peptide of human MACC1
• Target NameMACC1
• Alternative Names    7A5; SH3BP4L
• Accession No. Swiss-Prot#: Q6ZN28
  Gene ID: 346389
• UniprotQ6ZN28
• Gene ID346389;
• Concentration 1.6mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• 
  Immunohistochemistry: 1:25-1:100

MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409)-HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival?

• Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using #43136 at dilution 1/25,

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting