• Product NameRecombinant Human TLE1
• Brief DescriptionRecombinant Protein
• Immunogen DescriptionFusion protein corresponding to a region derived from 571-770 amino acids of human TLE1
• Target Nametransducin like enhancer of split 1
• Alternative Names    ESG; ESG1; GRG1
• Accession No. Swissprot:Q04724
  Gene Accession:BC015747
• UniprotQ04724
• Gene ID7088;
• Storage -20~-80˚C, pH 7.6 PBS

Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.

Note: For in vitro research use only, not for diagnostic or therapeutic use. This product is not a medical device.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting