• Product NameRecombinant Human EIF4E2
• Brief DescriptionRecombinant Protein
• Immunogen DescriptionFusion protein corresponding to a region derived from 1-245 amino acids of human EIF4E2
• Target Nameeukaryotic translation initiation factor 4E family member 2
• Alternative Names    4EHP; IF4e; 4E-LP; h4EHP; EIF4EL3
• Accession No. Swissprot:O60573
  Gene Accession:BC005392
• UniprotO60573
• Gene ID9470;
• Storage -20~-80˚C, pH 7.6 PBS

Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation (PubMed:9582349, PubMed:17368478, PubMed:25624349). Acts as a repressor of translation initiation (PubMed:22751931). In contrast to EIF4E, it is unable to bind eIF4G (EIF4G1, EIF4G2 or EIF4G3), suggesting that it acts by competing with EIF4E and block assembly of eIF4F at the cap (By similarity).

Note: For in vitro research use only, not for diagnostic or therapeutic use. This product is not a medical device.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting