• Product NameWRAP53 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsWB IHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total WRAP53 protein.
• Immunogen Typeprotein
• Immunogen DescriptionFusion protein of human WRAP53
• Target NameWRAP53
• Alternative Names    DKCB3; TCAB1; WDR79
• Accession No. Swiss-Prot#: Q9BUR4
  Gene ID: 55135
• UniprotQ9BUR4
• Gene ID55135;
• Calculated MW 59kd
• Concentration 1mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Western blotting: 1:200-1:1000
  Immunohistochemistry: 1:10-1:50

This gene encodes an essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex required for telomere synthesis. This protein is enriched in Cajal bodies, nuclear sites of RNP processing that are important for telomerase function. It interacts with dyskerin, TERT and TERC, other components of active telomerase, and with small Cajal body RNAs (scaRNAs), which are involved in modifying splicing RNAs.?

• Gel: 8%SDS-PAGE
  Lysate: 40 μg
  Lane 1-3: HT-29, hela and A431 cell
  Primary antibody: 1/400 dilution
  Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution
  Exposure time: 10 seconds
• Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue using #43348 at dilution 1/20,

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting