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PDHK1(Phospho-Tyr243) Antibody #11597

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Catalog No. Package Size Price Quantity
50ul $219.00
100ul $319.00
Availability:Yes
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Description
  • Product NamePDHK1(Phospho-Tyr243) Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
  • ApplicationsWB
  • Species ReactivityHu Rt
  • SpecificityThe antibody detects endogenous level of PDHK1 only when phosphorylated at tyrosine 243.
  • Immunogen TypePeptide-KLH
  • Immunogen DescriptionPeptide sequence around phosphorylation site of tyrosine 243(D-L-Y(p)-Y-I) derived from Human PDHK1.
  • Target NamePDHK1
  • ModificationPhospho
  • Alternative Names    PDK1; PDH kinase 1
  • Accession No. Swiss-Prot: Q15118
    NCBI Protein: NP_001265478.1
  • UniprotQ15118
  • Gene ID5163;
  • Target Species Human
  • Calculated MW 49kd
  • Concentration 1.0mg/mL
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Background

Published Papers

Pyruvate dehydrogenase inactivation causes glycolytic phenotype in BAP1 mutant uveal melanoma. In Oncogene on 2022 Feb by Anna Han, Vivian Chua,et al..PMID:35046531, , (2022),
PMID: 35046531
Mitochondria-Translocated PGK1 Functions as a Protein Kinase to Coordinate Glycolysis and the TCA Cycle in Tumorigenesis., , (2016 Mar),
PMID: 26942675
Please let us know if you have published research using #11597 so that we can cite your reference.

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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep