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KHK Isoform C Antibody #21709

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Catalog No. Package Size Price Quantity
50ul $219.00
100ul $319.00
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Description
  • Product NameKHK Isoform C Antibody
  • PurificationAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • ApplicationsWB IHC
  • Species ReactivityHu
  • SpecificityThe antibody detects endogenous level of total KHK Isoform C protein.
  • Immunogen DescriptionPeptide sequence around aa.102~106 (N-N-S-N-G) derived from Human KHK Isoform C.
  • Alternative Names    Ketohexokinase; Hepatic fructokinase; KHK
  • Accession No. Swiss-Prot#: P50053-1
    NCBI Gene ID: 3795
    NCBI Protein#: NP_000212.1
  • UniprotP50053
  • Gene ID3795;
  • Concentration 1.0mg/mL
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C
Application Details
Background

Published Papers

Non-hematopoietic IL-4Rα expression contributes to fructose-driven obesity and metabolic sequelae. In Int J Obes (Lond) on 2021 Nov by Michelle S M A Damen, Traci E Stankiewicz,et al..PMID:34302121, , (2021),
PMID: 34302121
Ketohexokinase inhibition improves NASH by reducing fructose-induced steatosis and fibrogenesis. In JHEP Rep on 2020 Nov 20 by Emma L Shepherd, Raquel Saborano, et al..PMID:33490936, , (2021),
PMID: 33490936
The small intestine shields the liver from fructose-induced steatosis. In Nat Metab on 2020 Jul by Cholsoon Jang, Shogo Wada, et al..PMID: 32694791, , (2020),
PMID: 32694791
Ketohexokinase-A acts as a nuclear protein kinase that mediates fructose-induced metastasis in breast cancer. In Nat Commun on 2020 Oct 28 by Jiyoung Kim, Jengmin Kang, et al..PMID:33116123, , (2020),
PMID: 33116123
View All Published Papers Deletion of Fructokinase in the Liver or in the Intestine Reveals Differential Effects on Sugar-Induced Metabolic Dysfunction. In Cell Metab on 2020 Jul 7 by Ana Andres-Hernando, David J Orlicky, et al..PMID:32502381, , (2020),
PMID: 32502381
The RNA-Binding Protein A1CF Regulates Hepatic Fructose and Glycerol Metabolism via Alternative RNA Splicing. In Cell Rep on 2019 Oct 8 by Kostas C Nikolaou, Hasan Vatandaslar, et al..PMID: 31597092 , , (2019),
PMID: 31597092
A splicing switch from ketohexokinase-C to ketohexokinase-A drives hepatocellular carcinoma formation.In Nat Cell Biol on 2016 Ma by Xinjian Li , Xu Qian et al..PMID:27088854 , , (2016 May),
PMID: 27088854
A splicing switch from ketohexokinase-C to ketohexokinase-A drives hepatocellular carcinoma formation.In Nat Cell Biol on 2016 Ma by Xinjian Li , Xu Qian et al..PMID:27088854 , , (2016),
PMID: 27088854
Please let us know if you have published research using #21709 so that we can cite your reference.

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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep