• Product NameZFP36 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total ZFP36 protein.
• Immunogen Typeprotein
• Immunogen DescriptionFusion protein of human ZFP36
• Target NameZFP36
• Alternative Names    TTP; G0S24; GOS24; TIS11; NUP475; zfp-36; RNF162A
• Accession No. Swiss-Prot#: P26651
  NCBI Gene ID: 7538
• UniprotP26651
• Gene ID7538;
• Concentration 1.3mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• 
  Immunohistochemistry: 1: 100-200

mRNA-binding protein involved in post-transcriptional regulation of AU-rich element (ARE)-containing mRNAs. Acts by specifically binding ARE-containing mRNAs and promoting their degradation. Recruits deadenylase CNOT7 (and probably the CCR4-NOT complex) via association with CNOT1. Plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF). Plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF).

• The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using ZFP36 Antibody at dilution 1/100, on the right is treated with fusion protein. (Original magnification: x200)
• The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using ZFP36 Antibody at dilution 1/100, on the right is treated with fusion protein. (Original magnification: x200)

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting