• Product NameXAF1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total XAF1 protein.
• Immunogen Typepeptide
• Immunogen DescriptionSynthetic peptide of human XAF1
• Target NameXAF1
• Alternative Names    BIRC4BP; XIAPAF1; HSXIAPAF1
• Accession No. Swiss-Prot#: Q6GPH4
  NCBI Gene ID: 54739
• UniprotQ6GPH4
• Gene ID54739;
• Concentration 0.7mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• 
  Immunohistochemistry: 1: 10-50

This gene encodes a protein which binds to and counteracts the inhibitory effect of a member of the IAP (inhibitor of apoptosis) protein family. IAP proteins bind to and inhibit caspases which are activated during apoptosis. The proportion of IAPs and proteins which interfere with their activity, such as the encoded protein, affect the progress of the apoptosis signaling pathway. Multiple transcript variants encoding different isoforms have been found for this gene.?

• The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using XAF1 Antibody at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200)
• The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using XAF1 Antibody at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200)

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting