SAMD9L(sterile α motif domain containing 9-like), also known as UEF1,DRIF2 or C7orf6, is a 1,584 amino acid protein thatcontains one N-terminal sterileαmotif (SAM) domain. Expressed in a variety of adult and fetal tissues, SAMD9Lmay be involved (via its SAMdomain) in protein-protein interactions, playing a role in biological processes(such as developmental regulation) throughout the body. Orthologs of SAMDL9 are present in nearly allspecies with the exception of fish,chicken and frog, implying a conserved function in higher eukaryotes.