• Product NameTNFRSF10A Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total TNFRSF10A protein.
• Immunogen Typepeptide
• Immunogen DescriptionSynthetic peptide of human TNFRSF10A
• Target NameTNFRSF10A
• Alternative Names    DR4; APO2; CD261; TRAILR1; TRAILR-1
• Accession No. Swiss-Prot#: O00220
  NCBI Gene ID: 8797
• UniprotO00220
• Gene ID8797;
• Concentration 0.2mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• 
  Immunohistochemistry: 1: 20-100

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.?

• The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TNFRSF10A Antibody at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200)

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting